General Information:

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Magaldrate is a common antacid drug that is used for the treatment of gastro esophageal reflux. Magaldrate has a variable composition corresponding approximately to Al5Mg10(OH)31(SO4)2.xH2O and contains Mg(OH)2 content Between 49.2 % to 66.6 % on Dried Basis and Between 32.1 % to 45.9 % Al(OH)3 content on Dried Basis and Between 16.0 % to 21.0 % SO4 content on Dried Basis and Between 90% to 105% of Al5Mg10(OH)31(SO4)2 Assay on Dried Basis.

Molecular Structure:

Nomenclature:

  • CAS No.: 74978-16-8
  • Molecular Formula: Al5Mg10(OH)31(SO4)2, x. H2O
  • Molecular Weight: 1097.38 gm/mol
  • Synonyms: Aluminium Magnesium Hydroxide Sulfate

Physical Property:

  • Physical state: White or almost white, crystalline powder
  • Solubility: Practically insoluble in water and in ethanol (96%). It is soluble in dilute mineral acids
  • PH: 8.0 – 10.5 (5 % Aqueous solution)

Application & Use:

Magaldrate is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.Magaldrate is a hydrated complex of hydroxy magnesium aluminate. It initially reacts rapidly with acid and releases aluminium hydroxide which then acts more slowly. The freshly released alum hydroxide is in the impolymerized, more reactive form. It is a good antacid with prompt and sustained neutralizing action. Simethicone when added offers additional benefit by preventing flatulence development.

Advantage and Disadvantage:

Magaldrate is used to treat a sour stomach, acid indigestion, heartburn and gas. It is an antacid that neutralizes the stomach acid and slowly increases the pH level of the stomach.There are very few possible side effects of Magaldrate that include intestinal pain, constipation and diarrhea. More serious side effects that need medical attention are loss of appetite, tarry stools, slow reflexes, vomiting and rashes.

Shelf Life

Expiry:5 Years after date of manufacture

Quality Assurance / Certificate

WHO-GMP: Par Drugs And Chemicals Limited is WHO GMP Certified.
(Issued by Food & Drug Control Administration)
Note: Above Certificate is available upon request.

Certificate of Compliance

GMO: The Product does not contain any Genetically Modified Organisms (GMO) of raw materials used in manufacturing of the same are also not genetically modified.
Non-Irradiation:The product was never subjected to any kind of ionized irradiation and contains no radioactivity not even in minor amounts.
Allergens: The product does not contain any of the below mentioned allergens:
Cereals containing Gluten, Crustaceans, Eggs, Fish, Peanuts, Treenuts, Soybeans, Milk, Sesame seeds, Sulphur Dioxide ands sulphites (concentration > 10 mg/kg), Lupin, Molluscs.
TSE/BSE: The Product is not derived from animal/plant origin & hence this product is free from Transmissible Spongiform Encephalopathy (TSE) and Bovine Spongiform Encephalopathy (BSE). It is synthetically derived
Residual Solvent: Class1, Class 2, Class 3 & Table 4 solvents are not used in the production of our product.
Vegetarians / Vegans: Our product is suitable for consumption by vegetarians and vegans.

Storage Recommendations

Store Protected From Moisture

Packaging

25 kg net weight packed in LDPE Liner follow by HDPE Woven Bag.

Specifications

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