MAGALDRATE IP

CAS  No. : 74978-16-8
Molecular Formula : Al5Mg10(OH)31(SO4)2, xH2O
Molecular Weight  : 1097.40 gm/mol
Category : Antacid
Storage Condition : Store protected from moisture
Source : IP-2010 Vol-2, Page No.1617

Application

Used as an Antacid Raw material in a specific antacid formulations.

Sr. No. Test Parameters Specification / Limits
1 Description White or almost white crystalline powder, odourless.
2 Solubility Insoluble in water and in ethanol (95%), Soluble in dilute solution of mineral acids.
3 Identification (A)
(B)
It gives the reaction of magnesium salts.
It gives the reaction of aluminium salts.
4 Arsenic Not more than 10 ppm
5 Heavy Metals Not more than 60 ppm
6 Soluble Chloride Not more than 3.5 %
7 Soluble Sulphate Not more than 1.9 %
8 Sodium Not more than 2.2 µg Na per ml.
9 Loss on Drying Between: 10.0 % to 20.0 %
10 Al (OH)3
(Dried Basis)  
Between 32.1 % to 45.9 %
11 Mg(OH)2
(Dried Basis)
Between 49.2 % to 66.6 %
12 Sulphate
(Dried Basis)
Between 16% to 21%
13 Microbial Limits:
E-Coli:

Absent per gm
14 Assay (Dried basis) Between 90% to 105% of Al5Mg10(OH)31(SO4)2

MAGALDRATE USP

CAS  No. : 74978-16-8
Molecular Formula : Al5Mg10(OH)31(SO4)2.xH2O
Molecular Weight  : 1097.38 gm/mol
Storage Condition : Preserve in well-closed container
Source : USP-34, Page No. 3355

Application

Used as an Antacid Raw material in a specific antacid formulations.

Sr. No. Test Parameters Limit
1 Description White, odourless, crystalline powder.
2 Solubility Insoluble in water and in alcohol, soluble in dilute solutions of mineral acids.
3 Identification: (A)
(B)
(C)
It gives the reaction of magnesium.
It gives the reaction of aluminium.
By X- ray diffraction confirms to that of reference standard (at 2.57 angstrom units)
4 Microbial Limits:
E-Coli
Absent per gm
5 Loss on Drying Between 10 % to 20 % dried at 200° for 4 hours
6 Soluble chloride Not more than 3.5 %
7 Soluble sulphate Not more than 1.9 %
8 Sodium Not more than 0.11 %
9 Arsenic Not more than 8 ppm
10 Heavy Metals Not more than 0.006 %
11 Mg(OH)2 content
(Dried Basis)
Between 49.2 % to 66.6 %
12 Al(OH)3 content
(Dried Basis)
Between 32.1 % to 45.9 %
13 SO4 content
(Dried Basis)
Between 16.0 % to 21.0 %
14 Assay
(Dried Basis)
Between 90% to 105% of Al5Mg10(OH)31(SO4)2

MAGALDRATE BP

CAS  No. : 74978-16-8
Molecular Formula : Al5Mg10(OH)31(SO4)2
Molecular Weight  : 1097.00 gm/mol
Source : BP-2013

Application

Used as an Antacid Raw material in a specific antacid formulations.

Sr. No. Test Parameters Limit
1 Description White or almost white crystalline powder.
2 Solubility Practically insoluble in water and in alcohol, soluble in dilute mineral acids.
3 Identification: (A)
(B)
(C)
White crystalline precipitate is produced which does not dissolve in dilute ammonia solution.
It gives the reaction of aluminium.
It gives the reaction of sulphates.
4 Soluble Chloride Not more than 3.5 %
5 Soluble Sulphate Not more than 1.9 %
6 Sulphate Between 16 % to 21 %
7 Al (OH)3
(Dried Basis)
Between 32.1 % to 45.9 %
8 Mg(OH)2
(Dried Basis)
Between 49.2 % to 66.6 %
9 Sodium (By AAS) Not more than 0.10 %
10 Heavy Metals Not more than 30 ppm
11 Loss on Drying Between: 10.0 % to 20.0 % at 200° C
12 Assay (Dried Basis) Between 90% to 105% of Al5Mg10(OH)31(SO4)2


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